Immunological Relationships of Cell Constituents of Pneumococcus
نویسندگان
چکیده
In this paper the general immunological significance of the intact pneumococcus cell and of its protein and carbohydrate components is discussed.
منابع مشابه
Immunological Reactions of the Isolated Carbohydrate and Protein of Pneumococcus
The data presented in this paper clearly indicate that the isolated carbohydrate and nucleoprotein constituents of Pneumococcus differ both serologically and antigenically one from the other. Moreover, each of these fractions of the cell separately exhibits immunological properties distinct from those manifested by the whole organism of which they form a part. The carbohydrate is a protein-free...
متن کاملThe Immunological Properties of the Heterophile Antigen and Somatic Polysaccharide of Pneumococcus
1. The lipocarbohydrate or F polysaccharide derived from a rough variant of Type I pneumococcus (I R) is antigenic in rabbits and gives rise to precipitins and sheep cell hemolysins. The somatic or C carbohydrate on the other hand is not antigenic. 2. Antisera for the rough variant of Type 1 pneumococcus contain also bacterial agglutinins immunologically unrelated to the C and F precipitins and...
متن کاملX. Immunological Distinctions between the Hemotoxin and the "protein Fraction" of the Pneumococcus Cell. By
I t is known (1, 2) tha t the hemotoxin and the "prote in f rac t ion ' " of the pneumococcus cell possess the following propert ies in common: (1) bo th are cellular const i tuents of Pneumococcus and are present in solutions prepared from pneumococcus cells; (2) both react with species-specific, ra ther than type-specific antibodies; (3) antibodies (ant ihemotoxin and precipitins) react ive w...
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Previous papers (1, 2) reported evidence of immunological relationship between a variety of Saccharomyces cerevisi.ae (yeast) and the Type I I variety of Diplococcus pneumoniae (pneumococcus). The relationship, apparently dependent upon S-anti-S reactions, was evidenced by the immunological reactions of agglutination and of passive protection in which the test antigens were the whole cells of t...
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Avery and Cullen (I, 2)have demonstrated that the pneumococcus cell contains the hydrolyzing enzymes (peptonase, lipase, sucrase, amylase, inulase) and a bacteriolytic enzyme. Cole (3) (1912), (4) (1914), has shown that pneumococci also possess a hemotoxin. These enzymes and the hemotoxin are endocellular, representing actual constituents of the cell, and consequently are demonstrable in steril...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 38 شماره
صفحات -
تاریخ انتشار 2003